Evolution and Trends of Scientific Entrepreneurship in the Health Sector in Spain
Spain currently ranks 9th worldwide in scientific publications, yet only 28th in the Global Innovation Index. On key research and innovation indicators, the country falls 11% below the European average. This disparity raises an important question: why does Spain struggle to translate research strength into innovation performance?
The challenge is not a lack of research capacity. Spain has a solid scientific ecosystem, producing high-quality knowledge and talent. The issue lies moving innovations from the lab to the market. To strengthen its economy, Spain needs more effective technology transfer, stronger collaboration between research institutions and industry, and greater flows of investment into innovation-driven ventures.
It is in response to this need that Fundación Botín and Inveniam Group created this report. The aim is to provide a clearer picture of Spain’s innovation ecosystem—mapping investment opportunities, identifying gaps, and tracking the entrepreneurial landscape—so that stakeholders can work together to drive sustainable growth.
Key Findings and Objectives
The report shows encouraging signs: since 2017, Spain’s innovation indicators have been on an upward trajectory. However, sustained effort is required to close the gap between scientific output and commercial impact.
This work is designed to serve as a reference tool for researchers, policymakers, investors, and innovation stakeholders. It highlights where resources and support should be directed and offers insights into how Spain can accelerate progress.
The report pursues three main objectives:
- Tracking spin-offs
- We compiled data from Technology Transfer Offices (TTOs), public agencies, press sources, and specialized platforms to map the creation and evolution of spin-offs across Spain, with a particular focus on the health sector.
- This effort identifies regional trends, strengths, and gaps in the innovation landscape.
- Examining exit operations
- We analyzed the number, timing, and location of exit events to understand investment pathways and the maturity of different sectors.
- By tracking where successful exits are happening, the report highlights regions with strong innovation performance and others with untapped potential.
- Assessing support structures
- We evaluated the role of TTOs and other support agents in facilitating technology transfer.
- The findings provide insight into how stronger connections between science, policy, and capital can be established.
A central outcome of this effort will be the creation of a spin-off database, mapping more than 20 years of activity. This will be the first database dedicated to healthcare innovation in Spain, designed as a tool to inform strategy, guide funding decisions, and foster collaboration.
Building a Stronger Ecosystem
The ultimate goal of this initiative is to strengthen Spain’s innovation ecosystem. To move closer to its full innovation potential, Spain must identify best practices, support technology transfer and align science with entrepreneurship and investment.
This report offers a snapshot of the current state of play, but above all, it is a call to action. With coordinated efforts and strategic investment, Spain can bridge the gap between scientific excellence and commercial success and generate tangible benefits for society and the economy.
