Each year, hundreds of millions of patients around the world are affected by health care-associated infections (HCAIs). Hand Hygiene has been proven the most efficient method to reduce HCAIs. However, compliance with hand hygiene practices among health care workers (HCW) has been very low. The World Health Organization (WHO) has proposed the Five Moments for Hand Hygiene, within the WHO Guidelines on Hand Hygiene in Health Care. This new technology is an automatic wireless monitoring system that allows to track and record the five moments to assure compliance. This new invention incorporates ICT technologies such as radio frequency devices and time of flight cameras. It enables tracking with high precision the interactions of the health care workers with their patients and hand hygiene devices, therefore monitoring and reminding the HWC to comply with hand hygiene.